Age - related Changes in Glutathione Concentration , Glutathione Peroxidase , Glutathione - S - Transferase , and Superoxide Dismutase Actiyities in Senescence Accelerated Mice
نویسنده
چکیده
Age-associated changes in several antioxidative factors were studied in blood and liver from mice prone to accelerated senescence aged O.7 to 1.4 years and mice resistant to acce]erated senescence aged 1.0 to 2.1 years. In both strains, actiyities of hepatic glutathione peroxidase (GSH-Px) and glutathione-Stransferase (GST) decrefised significantly with age, and the actiyity of superoxide dismutase (SOD), and
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Submit Manuscript | http://medcraveonline.com Abbreviations: ANOVA: Analysis of Variance; CAT: Catalase; GSH: Glutathione; GSSG: Oxidized Glutathione; GPx: Glutathione Peroxidase; GR: Glutathione Reductase; LPO: Lipid Peroxidation; Lipofuscin (LIF); ROS: Reactive Oxygen Species; SOD: Superoxide Dismutase; PMS: Phenazinemethosulphate; NBT: Nitoblu Tetrazolium; YC: Young Control; YEx: Young Exper...
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